Description
Prevention and Treatment of Travel Sickness and Motion-Related Nausea
Avomine Tablets 25mg Overview
Avomine Tablets 25 mg are an antihistamine medicine used to prevent and treat travel sickness (motion sickness) and associated nausea and vomiting. They are commonly taken before journeys by car, boat, plane or train to help reduce symptoms such as dizziness, nausea and vomiting.
In the UK, Avomine is an over-the-counter pharmacy medicine, suitable for adults and children over the recommended age when used as directed.
Understanding Motion Sickness
Why travel sickness occurs
Travel sickness occurs when the brain receives conflicting signals from the inner ear (vestibular system), eyes and body. This sensory mismatch can trigger nausea, dizziness, sweating and vomiting.
Motion sickness is more common during:
- sea travel
- winding road journeys
- turbulence during flights
- situations with limited visual reference
Why antihistamines are effective
Certain antihistamines help reduce motion sickness by blocking signals from the inner ear to the vomiting centre in the brain, reducing nausea and dizziness.
What Are Avomine Tablets?
Avomine Tablets contain promethazine teoclate, a first-generation antihistamine with anti-emetic (anti-sickness) properties. In addition to preventing nausea, promethazine has a mild sedative effect, which can help reduce the discomfort associated with motion sensitivity.
Avomine is often chosen for longer journeys, where sustained symptom control is required.
How Does Avomine Work?
Action on the inner ear and brain
Promethazine blocks histamine H1 receptors involved in motion-related nausea. This:
- reduces dizziness
- suppresses nausea
- helps prevent vomiting
Its sedative effect can also help reduce awareness of motion.
Duration of action
Avomine has a long duration of action, meaning a single dose may provide protection for several hours, depending on individual response.
What Avomine Helps With — and What It Does Not
What it helps with
Avomine Tablets are used to prevent and treat:
- travel sickness
- motion-related nausea
- vomiting associated with movement
- dizziness during travel
They are most effective when taken before symptoms begin.
What it does not treat
Avomine does not:
- treat nausea caused by infection or food poisoning
- cure inner ear disorders
- replace medical assessment for persistent vomiting
- prevent dehydration caused by vomiting
Other causes of nausea may require different treatment.
Who Are Avomine Tablets For?
Avomine may be suitable for:
- adults prone to travel sickness
- children over the recommended age (check product guidance)
- people undertaking long journeys
- individuals who find other travel sickness remedies ineffective
A pharmacist can advise on dosing and suitability.
Who Should Avoid Avomine
Avomine should not be used if:
- you are allergic to promethazine or similar antihistamines
- you have glaucoma or difficulty urinating due to prostate enlargement
- you are taking other sedating medicines without advice
Caution is advised in older adults and people with asthma or epilepsy.
How to Take Avomine Tablets
Avomine is usually taken 1–2 hours before travel. Tablets should be swallowed with water. Do not exceed the recommended dose.
Because Avomine can cause drowsiness, avoid alcohol and driving after taking it.
Safety, Warnings and Side Effects
Avomine commonly causes drowsiness, which may persist into the following day. Other possible side effects include dry mouth, blurred vision or constipation.
If excessive sedation or confusion occurs, stop use and seek advice.
When to Seek Medical Advice
Speak to a GP or pharmacist if:
- nausea or vomiting persists despite treatment
- symptoms occur without travel
- side effects are troublesome
- Avomine is needed frequently
Further assessment may be required.
Use in Pregnancy and Breastfeeding
Avomine should be used during pregnancy or breastfeeding only on professional advice, as antihistamines should be assessed on an individual basis.
How Avomine Compares to Other Travel Sickness Treatments
Avomine vs hyoscine
Hyoscine acts faster but for a shorter duration. Avomine offers longer-lasting protection for extended journeys.
Avomine vs non-drowsy antihistamines
Non-drowsy antihistamines are generally ineffective for motion sickness. Avomine’s sedating effect contributes to its anti-sickness action.
Avomine Tablets 25mg Summary
Avomine Tablets 25 mg provide effective, long-lasting protection against travel sickness, helping prevent nausea, vomiting and dizziness associated with motion. When taken correctly before travel, they can significantly improve comfort during journeys.
Persistent or unexplained nausea should always be assessed by a healthcare professional.





