Description
Overview
How Nurofen Day & Night Cold & Flu (16 Tablets) provide 24-hour relief Nurofen Day & Night Cold & Flu (16 Tablets) are designed to address the changing needs of a cold sufferer throughout the 24-hour cycle. The requirements for symptom relief during the day are different from those at night, and this pack contains two distinct formulations to reflect that. The yellow “Day” tablets contain a combination of ibuprofen and phenylephrine hydrochloride. Ibuprofen targets the systemic inflammatory response caused by the viral infection. It inhibits the production of prostaglandins, which are the chemicals responsible for fever, body aches, and headaches. Simultaneously, phenylephrine hydrochloride acts as a vasoconstrictor. It works by stimulating the alpha-adrenergic receptors in the blood vessels of the nasal passages, causing them to narrow. This reduces the swelling of the mucous membranes and relieves congestion, allowing the user to function effectively without a blocked nose during waking hours.
Why Nurofen Day & Night Cold & Flu (16 Tablets) have a specific night formula The white “Night” tablets in the Nurofen Day & Night Cold & Flu (16 Tablets) pack are formulated specifically to support restful sleep, which is essential for immune recovery. Decongestants like phenylephrine can sometimes have a mild stimulating effect, which may cause wakefulness or difficulty drifting off if taken late in the evening. To prevent this, the Night tablets contain 200mg of ibuprofen but do not contain phenylephrine. This ensures that the user continues to receive effective relief from fever and pain, such as sore throats and headaches, throughout the night but without the risk of stimulation that could disrupt sleep quality.
The anti-inflammatory action of Nurofen Day & Night Cold & Flu (16 Tablets) Unlike paracetamol-based remedies that primarily block pain signals in the brain, the ibuprofen in Nurofen Day & Night Cold & Flu (16 Tablets) works at the site of the infection. It blocks the cyclooxygenase enzymes that drive inflammation. This is particularly beneficial for treating the physical symptoms of a cold, such as swollen sinuses that are tender to the touch or an inflamed pharynx that causes swallowing difficulties. By reducing this inflammation directly, Nurofen Day & Night Cold & Flu (16 Tablets) provide a deep level of relief from the heavy, pressured feeling often associated with flu-like illnesses.
Who Is It For
Who are Nurofen Day & Night Cold & Flu (16 Tablets) suitable for? Nurofen Day & Night Cold & Flu (16 Tablets) are suitable for adults and children aged 12 years and over. This product is specifically designed for individuals who require a non-drowsy decongestant to stay active during the day but who are sensitive to stimulants or simply want to ensure a restful night’s sleep. It is an ideal solution for those who find that standard all-day decongestants affect their ability to drift off at night.
Usage Instructions
How to take Nurofen Day & Night Cold & Flu (16 Tablets) correctly? The tablets should be swallowed whole with water and should not be chewed. It is important to distinguish between the two tablet types included in the pack.
Day Dosage: Adults and children aged 12 years and over should take one yellow Day tablet three times a day, with an interval of at least 4 hours between doses.
Night Dosage: Adults and children aged 12 years and over should take one white Night tablet before going to bed.
Dietary and timing requirements Nurofen Day & Night Cold & Flu (16 Tablets) must be taken with food or immediately after eating. Ibuprofen can be irritating to the stomach lining, and taking it with food helps to buffer the gastric mucosa against acid erosion and reduces the risk of indigestion or discomfort.
What are the dosage limits? The maximum dose is 3 Day tablets and 1 Night tablet in any 24-hour period. Users must not take more than this amount, as exceeding the dose of ibuprofen can lead to toxicity. Nurofen Day & Night Cold & Flu (16 Tablets) are for short-term use only and should not be taken for longer than 3 days without medical advice.
Warnings
When must Nurofen Day & Night Cold & Flu (16 Tablets) not be used? Nurofen Day & Night Cold & Flu (16 Tablets) must not be used by patients with a history of peptic ulcers or gastrointestinal bleeding. Due to the phenylephrine content in the Day tablets, the product is not suitable for individuals with severe high blood pressure, hyperthyroidism, or heart disease. Men with an enlarged prostate should avoid using Nurofen Day & Night Cold & Flu (16 Tablets), as the decongestant can make urination difficult. The product must not be used by anyone taking monoamine oxidase inhibitors for depression.
Safety advice regarding pregnancy Nurofen Day & Night Cold & Flu (16 Tablets) must not be taken during the last three months of pregnancy. The ibuprofen component can cause serious complications for the baby’s heart and kidneys and may delay labour. The use of phenylephrine is also generally advised against throughout pregnancy due to its effect on blood vessel constriction. Breastfeeding mothers should consult a doctor before use, although ibuprofen is generally considered safe, the decongestant may reduce milk supply.
Alternatives
Common alternatives to Nurofen Day & Night Cold & Flu (16 Tablets)? If Nurofen Day & Night Cold & Flu (16 Tablets) are not suitable due to the NSAID content or specific medical conditions, common alternatives include:
Sudafed Mucus Relief Day & Night Capsules: Contains paracetamol instead of ibuprofen, making it a suitable option for those with sensitive stomachs who still need a split day/night treatment regimen.
Day & Night Nurse Capsules: A combination pack providing a non-drowsy day capsule and a night capsule that contains a sedative antihistamine to actively promote sleep.
Otrivine Mucus Relief Nasal Spray: A xylometazoline spray that clears nasal congestion immediately through topical application, avoiding systemic side effects for those with high blood pressure.
Panadol Advance: Simple paracetamol tablets that effectively lower fever and treat pain without interacting with the stomach lining or cardiovascular system.





